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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: J Immunol. 2016 Mar 30;196(9):3677–3685. doi: 10.4049/jimmunol.1502709

Fig. 6. All CBP- Pn mutants, except for the ΔPspA Pn mutant, inhibited the cOVA-specific IgG response.

Fig. 6

BALB/c mice (7 per group) were immunized i.v. with 50 μg cOVA in alum with or without (A) 2×108 CFU R36A or T4R or T4R mutants for the respective CBPs listed in the graph. (B) 2×108 CFU T4R or T4R PspA mutant (ΔPspA). (C) 2×108 intact R36A, 50 μg recombinant, truncated PspA, or 50 μg recombinant full-length LytA. All mice were boosted i.v. with 50 μg cOVA in alum without bacteria, on d 14. Serum titers of cOVA-specific IgG were measured by ELISA. Significance * p<0.05.