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. Author manuscript; available in PMC: 2017 May 15.
Published in final edited form as: J Immunol. 2016 Apr 6;196(10):4196–4203. doi: 10.4049/jimmunol.1600081

Figure 3. Contribution of individual virulence factors to LAC-JE2 survival in the lower airways.

Figure 3

(A-B) Lung bacterial burdens at 5 h after infection of C57BL/6 mice with 107 CFU of LAC-JE2 WT in a 1:1 mixture with mutant agrA, crtQ (A), crtM (B) or hla (B). (C) Competitive survival of various LAC-JE2 mutants in the lungs 5 h after infection of C57BL/6 mice in a 1:1 mixture with crtQ mutant. Each symbol represents the fold change of CFU. **P< 0.01, ***P< 0.001, Tukey's multiple comparisons test. Data shown are combined from at least two independent experiments.