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. 2015 Dec 10;7(5):5313–5326. doi: 10.18632/oncotarget.6543

Figure 3. Neurogenes expression among breast cancer subtypes (MicMa Database) Tumor gene expression levels for 96 patients with different breast cancer subtypes.

Figure 3

Rows represent microarray probes corresponding to the selected genes (neurogenes differentially expressed in CD44+ cells) and columns represent patients. 3 independent gene set were identified and gathered. Orange square: genes upregulated in basal like patients: EDNRB, PDGFD, EGR3, NGFR, NRXN2, GRID1, PDGFRB. Blue squares: genes downregulated in basal like patients and upregulated in HER-2 enriched patients: PRKACA, PTPRES, SLC6A9, GPR25, SLC17A7, ABLIM2, CNTFR, ADORA1, GNG4, STX1A, CCL11, ECEL1, TAP2. Violet square: genes upregulated in basal and HER2-enriched patients: MME, DPYSL3, FEZ1, ID3, PDGFC, B2M, MAP2K1, NFATC3, RAP1A, NTRK3, HRH1, MET, GFRA2 APP, CDH2, NRP2, KLK1, RPS6KA3, RUNX3, GPR44, EFNB1. Red and green indicate high and low expression levels, respectively.