Table 1. Associations between candidate SNPs in the TERT-CLPTM1L locus and risk of ESCC in Jiangsu case-control set.

No.	rs ID	Position	Base change	MAF1	Genotype (588 cases and 600 controls)				P3
					Common2	Heterozygous2	Rare2	OR(95%CI)3
1	rs2853691	1305950	T>C	0.257	44.2/54.6	43.5/39.4	12.3/6.0	1.50 (1.25-1.80)	7.0 × 10−6
2	rs2736122	1310621	G>A	0.058	87.8/89.1	12.1/10.3	0.1/0.6	1.07 (0.75-1.52)	0.701
3	rs2075786	1319310	A>G	0.128	74.5/76.3	24.0/21.8	1.5/1.9	1.06 (0.83-1.36)	0.621
4	rs4246742	1320356	T>A	0.355	43.8/40.9	44.6/47.0	11.7/12.0	0.93 (0.78-1.10)	0.397
5	rs4975605	1328528	C>A	0.053	90.5/89.7	9.3/10.1	0.1/0.2	0.90 (0.61-1.33)	0.586
6	rs2736100	1339516	A>C	0.405	28.1/35.7	46.7/47.6	25.2/16.7	1.39 (1.17-1.64)	7.8 × 10−5
7	rs2853676	1341547	C>T	0.126	75.3/75.9	23.0/22.9	1.7/1.1	1.05 (0.82-1.35)	0.664
8	rs2736098	1347086	C>T	0.392	40.8/41.0	39.7/39.6	19.5/19.4	1.01 (0.85-1.19)	0.919
9	rs2853668	1353025	G>T	0.293	49.5/49.8	42.1/42.0	8.4/8.3	0.99 (0.83-1.19)	0.927
10	rs2735845	1353584	C>G	0.328	45.2/45.3	44.5/43.7	10.3/11.0	0.99 (0.83-1.18)	0.890
11	rs6554759	1370102	A>G	0.045	90.3/91.1	9.4/8.7	0.3/0.2	1.12 (0.76-1.66)	0.554
12	rs451360	1372680	C>A	0.117	83.9/78.2	15.3/20.2	0.8/1.6	0.69 (0.52-0.91)	0.007
13	rs380286	1373247	G>A	0.125	77.4/76.5	21.5/22.0	1.1/1.5	0.94 (0.73-1.21)	0.612
14	rs402710	1373722	C>T	0.325	44.5/45.8	44.9/43.4	10.6/10.8	1.03 (0.86-1.22)	0.764
15	rs452932	1383253	T>C	0.160	72.6/70.9	25.6/26.1	1.8/2.9	0.90 (0.71-1.13)	0.352

Note: ESCC, esophageal squamous cell carcinoma; MAF, minor allele frequency; OR, odds ratios; 95%CI, 95% confident intervals.

¹MAF in healthy controls.

²% of case/% of control.

³Allelic OR calculated by logistic regression.