Table 1. Liver and kidney damage (mean ± SD) in villagers from Guizhou Province (control and exposed groups).
| Group | As (mean ± SD) | Liver damage | Kidney damage | ||||
|---|---|---|---|---|---|---|---|
| Urine (μg/L) | Hair (μg/g) | A/G | ALT (U/L) | AST (U/L) | BUN (mmol/L) | CREA (μmol/L) | |
| Control | 20.8 ± 7.8 | 0.1 ± 0.07 | 1.6 ± 0.19 | 20.9 ± 4.9 | 28.3 ± 5.19 | 4.5 ± 0.82 | 68.0 ± 11.10 |
| Exposed | 45.4 ± 19.4** | 0.4 ± 0.2** | 1.3 ± 0.23** | 25.1 ± 11.80 | 35.3 ± 15.43 | 5.7 ± 1.18* | 63.4 ± 12.76 |
Abbreviations: As, arsenic; A/G, the ratio of albumin and globulin; ALT, glutamic-pyruvic transaminase; AST, glutamic-oxalacetic transaminase; BUN, blood urea nitrogen; CREA, creatinine.
**
P < 0.01, significantly different compared with the control group.
*
P < 0.05, significantly different compared with the control group
ICP-MS was used to measure both urinary arsenic and hair arsenic levels in all subjects.