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. 2015 Dec 22;7(5):5877–5891. doi: 10.18632/oncotarget.6711

Table 1. The cytotoxic effect of doxorubicin (DOX), DOX-loaded Tea nanoparticles (DOX-TNP) and TNP on CCD-18Co, SW620 and SW620/Ad300 cell lines.

Treatment CCD-18Co SW620 SW620/Ad300
IC50 ± SDa (μM) CRb IC50 ± SD (μM) CR IC50 ± SD (μM) CR
DOX 0.190 ± 0.015 [21.1] 0.077 ± 0.006 [8.6] 4.430 ± 0.190 [492.2]
DOX-TNP 0.043 ± 0.010 [4.8] 0.009 ± 0.001 [1.0] 0.852 ± 0.055 [94.7]
TNP > 300 μM > 300 μM > 300 μM
a

IC50: concentration that inhibited cell survival by 50% (means ± SD).

b

CR: cytotoxicity ratio was the value of IC50 value for DOX or DOX-loaded TNP on CCD-18Co, SW620 or SW620/Ad300 cells was divided by IC50 value for DOX-loaded TNP on SW620 cells.

Values in table are representative of at least three independent experiments performed in triplicate.