A decrease in the age-adjusted rate of HF for both men and women was observed between 2000 and 2010. This decrease is most notable for HRrEF. HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction. Modified from Gerber, Y. et al. A contemporary appraisal of the heart failure epidemic in Olmsted County, Minnesota, 2000 to 2010. JAMA Intern. Med.
175, 996–1004 (2015), with permission from the American Medical Association.