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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Kidney Int. 2016 Apr 28;89(6):1293–1306. doi: 10.1016/j.kint.2016.02.030

Figure 4. Expression of inflammatory mediator mRNA in kidney isografts and allografts in wild type C57BL/6, B6.CCR5−/− and B6.CD8−/−CCR5−/− recipients.

Figure 4

Groups of wild type C57BL/6, B6.CCR5−/− and B6.CD8−/−CCR5−/− mice (n = 4) received renal allografts from A/J donors and a group of wild type C57BL/6 mice received isografts (n = 4). Grafts were harvested on days 3, 7, and 14 post-transplant and at the time of the rejection. On the indicated day post-transplant, kidneys were harvested and whole cell RNA was prepared and analyzed by qRT/PCR for expression of the indicated neutrophil chemoattractant CXCL1 and CXCL2, T cell chemoattractant RANTES, and inflammatory mediator genes. Data indicate the mean expression levels for each group on the indicated day ± SEM. All significant differences are indicated by *P<0.05.