Structure of the CARP gene (ankrd1) and translated protein
(a) Ankrd1 sequence has 9 exons and several canonical response elements in the 5'-untranslated region, including the GATA-box, AT-rich, E-box, and TATA-box. (b) The CARP protein has 319 amino acids (aa) consisting of nuclear localization signals (NLSs) (71‒80 aa, 94‒103 aa), PEST-like regions (108‒126 aa), and four ankyrin-like repeats (152‒283 aa). CARP also contains six CASQ-2-binding sites and two titin-binding sites