Table 1.
Characteristics of men with PD and control group.
| Parameter | Prediabetes number 84 |
Control number 58 |
p ∗ |
|---|---|---|---|
| Age (years) | 66.5 ± 3.8 | 65.7 ± 3.8 | — |
| TT (nmol/L) | 11.24 ± 1.81 | 16.23 ± 1.6 | 0.001 |
| cFT (nmol/L) | 0.331 ± 0.08 | 0.387 ± 0.07 | 0.005 |
| DHEAS (ng/mL) | 542 (186–867) | 669 (229–943) | 0.02 |
| IGF-1, (ng/mL) | 87.3 ± 43.3 | 94.3 ± 41.9 | — |
| LH (IU/L) | 6.7 ± 0.9 | 4.4 ± 1.2 | 0.05 |
| FSH (IU/L) | 8.2 ± 1.1 | 7.9 ± 1.3 | — |
| Prolactin (ng/mL) | 11 ± 3.8 | 12 ± 3.7 | — |
| Estradiol (pg/mL) | 31.9 ± 8.2 | 28.6 ± 7.8 | 0.05 |
| SHBG (nmol/L) | 31.8 ± 3.2 | 27.7 ± 3.4 | 0.02 |
| Weight (kg) | 86.2 ± 7.45 | 84.8 ± 6.75 | — |
| BMI (kg/m2) | 28.6 ± 1.2 | 27.8 ± 0.9 | — |
| WC (cm) | 111 (103–115) | 98 (94–104) | 0.01 |
| HbA1c (%) | 6.2 ± 0.9 | 5.2 ± 1.2 | 0.02 |
| FPG (mg/dL) | 116 ± 6.6 | 92 ± 4.6 | 0.001 |
| Glucose in OGTT (mg/dL) | 148 ± 6.4 | 117 ± 6.6 | 0.05 |
| SBP (mmHg) | 146 ± 17.2 | 139 ± 17.3 | — |
| DBP (mmHg) | 94 ± 12.4 | 90 ± 8.7 | — |
| Cholesterol (mg/dL) | 225 ± 18 | 202 ± 17 | 0.05 |
| Triglycerides (mg/dL) | 162 ± 13 | 151 ± 14 | 0.05 |
| HDL-cholesterol (mg/dL) | 36 ± 4.6 | 39 ± 4.2 | — |
| LDL-cholesterol (mg/dL) | 146 ± 12 | 132 ± 13 | 0.02 |
|
| |||
| Comorbidities | |||
| Obesity, %; (number) | 71 (60) | 57 (33) | 0.02 |
| Current smoker, %, (number) | 32 (27) | 33 (19) | NS |
| Hypertension, %, (number) | 51 (43) | 38 (22) | 0.05 |
| MetS, %, (number) | 83 (70) | 67 (39) | 0.01 |
| CVD, %, (number) | 26 (22) | 19 (11) | 0.05 |
Data are presented as a mean ± standard deviation of the mean, a median (with lower and upper quartiles), or number (percentage), where appropriate. ∗ p shows differences between men with PD and control group. BMI: body mass index, WC: waist circumference, TT: total testosterone, cFT: calculated free testosterone, LH: luteinizing hormone, DHEAS: dehydroepiandrosterone sulfate, SHBG: sex hormone binding globulin, E2: estradiol, IGF-1: insulin-like growth factor 1, FPG: fasting plasma glucose, OGTT: oral glucose tolerance test, HbA1c: glycated hemoglobin, MetS: metabolic syndrome, CVD: cardiovascular disease, SBP: systolic blood pressure, and DBP: diastolic blood pressure.