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. 2016 May 17;6:26148. doi: 10.1038/srep26148

Table 2. Comparisons of functional connectivity of the parahippocampal seeds between aMCI patients and HC subjects.

Brain region Peak MNI coordinate
Peak Z value Cluster size (mm3)
x y z
The left PHG subregional networks
 (1) PRC (HC > aMCI)
  R Inferior temporal gyrus 52 2 −32 2.89 723
 (2) ERC (HC > aMCI)
  L Cerebelum_4_5 −8 −56 −2 3.31 752
  R Cerebelum_4_5 10 −52 −4 3.92 721
 (3) aPHC (HC > aMCI)
  R Middle temporal gyrus 52 2 −26 3.67 1336
 (4) pPHC (HC > aMCI)
  L Inferior temporal gyrus −62 −36 −14 3.30 960
  L Middle temporal gyrus −66 −30 −12 3.43 1560
  R Middle temporal gyrus 48 2 −30 3.60 1364
The right PHG subregional networks
 (1) PRC (HC > aMCI)
  R Hippocampus 20 −32 2 4.43 792
  R Inferior temporal gyrus 52 −4 −36 3.62 984
  L Thalamus −14 −34 2 3.57 624
(HC < aMCI)
  L Middle occipital gyrus −34 −78 26 −3.40 636
 (2) ERC (HC > aMCI)
  R Hippocampus 28 −30 −6 3.22 684
(HC < aMCI)
  L Inferior occipital gyrus −44 −66 −6 −3.37 682
 (3) aPHC (HC > aMCI)
  none          
 (4) pPHC (HC > aMCI)
  R Angular gyrus 42 −64 36 3.66 680
  L Cuneus −20 −58 26 3.90 616
  L Precuneus 0 −64 28 3.09 776
  R Precuneus 10 −50 34 3.16 1744
  R Middle temporal gyrus 60 −32 −8 3.41 784

Abbreviations: HC, healthy controls; aMCI, amnestic mild cognitive impairment; PRC, anterior perirhinal cortex; ERC, entorhinal cortex; aPHC, anterior parahippocampal cortex; pPHC, posterior parahippocampal cortex.