Table 3. Comparisons of functional connectivity of the hippocampus subregional seeds between aMCI patients and HC subjects.
Brain region | Peak MNI coordinate |
Peak Z value | Cluster size (mm3) | ||
---|---|---|---|---|---|
x | y | z | |||
The left HIP subregional networks | |||||
(1) aHIP (HC > aMCI) | |||||
none | |||||
(2) mHIP (HC > aMCI) | |||||
R Precuneus | 16 | −50 | 14 | 3.23 | 800 |
R Middle temporal gyrus | 60 | 4 | −30 | 3.80 | 1336 |
(3) pHIP (HC > aMCI) | |||||
none | |||||
The right HIP subregional networks | |||||
(1) aHIP (HC > aMCI) | |||||
R Fusiform gyrus | 38 | −52 | −14 | 3.79 | 872 |
(2) mHIP (HC > aMCI) | |||||
R Cerebelum_4_5 | 24 | −40 | −24 | 3.62 | 1720 |
R Fusiform gyrus | 24 | −40 | −16 | 3.75 | 1456 |
(3) pHIP (HC > aMCI) | |||||
R Fusiform gyrus | 30 | −2 | −40 | 3.29 | 744 |
Abbreviations: HC, healthy controls; aMCI, amnestic mild cognitive impairment; aHIP, anterior hippocampus; mHIP, middle hippocampus; pHIP, posterior hippocampus.