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. 2016 May 17;6:26096. doi: 10.1038/srep26096

Figure 6. Effect of electrical autapse in modulating irregular neuronal firing.

Figure 6

(A) The CVISI value (A1) and average output firing rate (A2) are plotted as a function of the input rate fin for the PEA and PAB models. (B) Typical MP traces and corresponding SC traces of the PEA model at different self-feedback levels. Similar to Fig. 4A, the red color in MP traces denotes the occurrence of burst firing, the gray lines in SC traces represent the total synaptic currents from presynaptic neurons, and the black lines in SC traces are the autaptic currents from the postsynaptic neuron. (C) ISI distribution curves for the PEA and PAB models, with the input rate fin = 40 Hz. (D) Burst frequency (D1) and burst size (D2) for the PEA and PAB models. In simulations, electrical coupling strengths are: Waut = 0 mS/cm2 (PAB), Waut = 0.2 mS/cm2 (PEA), Waut = 0.4 mS/cm2 (PEA) and Waut = 0.6 mS/cm2 (PEA). The black dashed lines in (D1) and (D2) represent the burst frequency and burst size of the PAB model, respectively.