Table 3.
The 10 most frequently reported medications used during pregnancy or during the month prior to pregnancy, and changes during pregnancy (rank ordered).
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Medications used during pregnancy or month prior to pregnancy | Rank order of top 10 medications | ||||||
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Medication | Changes during pregnancy | ||||||
| n/N | % | Rx | OTC | Not taken | Increased | Decreaseda | ||
| Antibiotic | ||||||||
| Pivmecillinam | 67/2065 | 3.24 | 5 |
|
|
|
|
|
| Antidepressants | ||||||||
| Citalopram | 34/2065 | 1.65 |
|
|
2 |
|
5 | |
| Fluoxetine | 30/2065 | 1.45 |
|
|
7 |
|
7 | |
| Sertraline | 39/2065 | 1.89 |
|
|
10b |
|
8 | |
| Antidiabetics | ||||||||
| Insulin aspart | 27/2065 | 1.30 |
|
|
|
5 |
|
|
| Metformin | 48/2065 | 2.32 | 9 |
|
10b |
|
|
|
| Antifungal | ||||||||
| Clotrimazole | 135/2065 | 6.54 |
|
5 |
|
|
||
| Anti-inflammatories and pain | ||||||||
| Acetylsalicyclic acid | 48/2065 | 2.32 |
|
|
|
6 |
|
|
| Diclofenac | 16/2065 | 0.77 |
|
|
6 |
|
10b | |
| Ibuprofen | 149/2065 | 7.21 |
|
4 | 1 |
|
1b | |
| Paracetamol | 1483/2065 | 71.82 |
|
1 | 4 | 4 | 1b | |
| Paracetamol combination | 80/2065 | 3.88 |
|
9 |
|
|
6 | |
| Tramadol | 28/2065 | 1.36 |
|
|
5 |
|
9 | |
| Anti-infectives | ||||||||
| Amoxicillin | 165/2065 | 8.00 | 1 |
|
|
|
|
|
| Fluconazole | 64/2065 | 3.10 | 6 |
|
|
|
|
|
| Antimigraine | ||||||||
| Sumatriptan | 31/2065 | 1.50 |
|
|
3 |
|
3b | |
| Digestive disorders | ||||||||
| Metoclopramide | 47/2065 | 2.28 | 10 |
|
|
|
|
|
|
|
Alginic acid | 291/2065 | 14.09 |
|
2 |
|
3 |
|
| Ispaghula (psylla seeds) | 90/2065 | 4.36 |
|
8 |
|
|
|
|
| Lactulose | 101/2065 | 4.89 |
|
6 |
|
|
|
|
| Omeprazole | 80/2065 | 3.88 |
|
10 |
|
9 |
|
|
| Ordinary salt combinations (eg, calcium carbonate) | 173/2065 | 8.37 |
|
3 |
|
|
|
|
| Ranitidine | 51/2065 | 2.46 |
|
|
|
7 |
|
|
| Ear, nose, and throat/decongestant | ||||||||
| Xylometazoline | 93/2065 | 4.50 |
|
7 |
|
|
|
|
| Reproductive | ||||||||
| Clomifene | 57/2065 | 2.76 | 8 |
|
|
|
|
|
| Ethinyl estradiol | 5/2065 | 0.24 |
|
|
9 |
|
|
|
| Hormonal contraceptives for systemic use | 73/2065 | 3.54 | 4c |
|
8 |
|
|
|
| Progesterone | 59/2065 | 2.86 | 7c |
|
|
|
|
|
| Respiratory | ||||||||
| Beclomethasone | 30/2065 | 1.45 |
|
|
|
8 |
|
|
| Salbutamol | 96/2065 | 4.64 | 2 |
|
|
2 | 3b | |
| Terbutaline | 32/2065 | 1.55 |
|
|
|
10 | 10b | |
| Thyroid | ||||||||
| Levothyroxine sodium | 83/2065 | 4.02 | 3 |
|
|
1 |
|
|
|
| ||||||||
aDecreased, but not stopped
bTied for place
cProbably represents use in the month before pregnancy