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. 2016 May 17;17:366. doi: 10.1186/s12864-016-2692-4

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© Trotta. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Synonymous codon fraction versus GC content. Relative frequencies of stop (right panel), GC-rich (left panel), and AU-rich (middle panel) synonymous codons in gene categories with increasing GC content. Red circles indicate the fraction of AU-rich codon (UGU) of the 2-fold degenerated cysteine family (UGC and UGU). Blue symbols indicate the fraction of AU-rich codons (GCA and GCU) of the 4-fold degenerate alanine family (GCA, GCC, GCG and GCU). Values in the right panel represent mean ± SEM