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. 2016 May 17;18:52. doi: 10.1186/s13058-016-0709-1

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© Baert et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Mean micronucleus (MN) yields and G₂/M checkpoint efficiency ratios obtained with the G₂ MN assay in healthy volunteers and BRCA1 mutation carriers. Significance was determined with a two-sided t test. p Values for each of the endpoints and dose points are indicated in the graph. Error bars represent the standard error of the mean. BN binucleated cell, Caf caffeine