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. 2016 May 17;16:204. doi: 10.1186/s12879-016-1550-y

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© Sandgren et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Flow chart of selection process. RQ: review question. LTBI: latent tuberculosis infection; TB: tuberculosis. Review question 1a: What is the initiation rate for each recommended LTBI treatment regimen?; Review question 1b: What is the completion rate for each recommended LTBI treatment regimen?; Review question 2a: What are the determinants of LTBI treatment initiation?; Review question 2b: What are the determinants of LTBI treatment adherence?; Review question 2c: What are the determinants of LTBI treatment completion?; Review question 3: In individuals who are eligible for LTBI treatment, what are the interventions with demonstrated efficacy or effectiveness to improve LTBI treatment initiation, adherence and completion?