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. 2016 May;5(2):90–96. doi: 10.5582/irdr.2016.01008

Table 1. Metabolic effects of viral infections.

Virus Metabolic effect Ref.
VACV, DENV Alteration of glycolysis, FAS, and glutaminolysis (15)
HCMV de novo pyrimidine biosynthetic flux in host cells (4)
HCMV, influenza A Inhibition of FAS, suppression of replication HCMV and influenza A (27)
HCMV Infection requirement of long chain FA metabolism: acyl-CoA synthetases and fatty acid elongases (18)
KSHV Inhibition of FAS and decrease in number of lytic enveloped viruses, induced apoptosis infected cells (10)
EBV, VZV, poliovirus, HCV Inhibition of FAS, lower number of infectious virus (2,3235)

This table summarizes the main effects that viral infections have over metabolism. VACV: vaccinia virus; DENV: Dengue virus; HCMV: Human Cytomegalovirus; KSHV: Kaposi's Sarcoma-associated herpesvirus; EBV: Epstein-Barr virus; HCV: Hepatitis C virus; FA: Fatty Acids; FAS: Fatty Acids Synthesis; TCA: tricarboxylic acid cycle.