. 2016 May 9;11:991–997. doi: 10.2147/COPD.S105988

Table 2.

Pulmonary function of patients with COPD, ACOS, and asthma FL⁺

	COPD (n=118)	ACOS (n=32)	Asthma FL⁺ (n=27)
VC, % predicted	98.70±1.70	95.57±3.05	101.34±3.07
FVC, % predicted	97.72±1.88	90.82±3.26	99.53±3.55
FEV₁, % predicted	69.84±1.85	63.43±3.22	76.28±2.54^*
FEV₁/FVC, %	56.97±1.01	55.98±1.66	61.06±1.28
PEFR, % predicted	69.67±2.09	61.08±3.54	74.40±3.16^*
MMF, % predicted	25.56±1.01	23.03±1.78	27.67±1.59
FRC, % predicted	100.98±2.04	104.74±3.65	111.30±6.61
RV, % predicted	137.38±3.43	148.46±6.25	112.05±4.34^,^*
TLC, % predicted	112.48±1.40	112.93±2.57	111.74±3.12
DLco, % predicted	64.93±2.15	70.67±3.68	85.70±3.19^,^**
DLco/VA, % predicted	80.51±2.55	85.70±4.12	118.50±4.06^,^*
Delta N₂, % N₂/L	3.21±0.20	2.63±0.35	2.35±0.24
CV/VC, %	20.41±1.28	18.23±1.95	16.76±2.12

Notes: Values are mean ± standard error of the mean. Delta N₂, slope of Phase III of the single breath nitrogen washout test.

^***

P<0.01 vs COPD.

^**

P<0.01.

P<0.05 vs ACOS.

Abbreviations: ACOS, asthma-COPD overlap syndrome; asthma FL⁺, asthma with airflow limitation; VC, vital capacity; FVC, forced vital capacity; FEV₁, forced expiratory volume in 1 second; PEFR, peak expiratory flow rate; MMF, maximum midexpiratory flow rate; FRC, functional residual capacity; RV, residual volume; TLC, total lung capacity; DLco, diffusing capacity for carbon monoxide; DLco/VA, diffusing capacity of lung for carbon monoxide corrected for alveolar volume; CV/VC, closing volume/vital capacity.