Table 1.
Patient characteristics
| Variables | NAVA (n=14) | Conventional (n=19) | P-value |
|---|---|---|---|
| Sex n(%) | |||
| Male | 11 (78.6%) | 13 (68.4%) | 0.51 |
| Female | 3 (21.4%) | 6 (31.6%) | |
| Age, years | 79.3±6.2 | 76.9±9.3 | 0.62 |
| IBW (Kg) | 53.6±11.2 | 55.7±1.7 | 0.82 |
| Total ICU, days | 19.4±11.8 | 22.3±19.4 | 0.08 |
| Ventilator days before | 26.9±10.7 | 27.1±13.0 | 0.41 |
| PFT (before admission) | |||
| FEV1/Pred (%) | 59.0±15.5 | 53.5±16.5 | 0.51 |
| FEV1/FVC (%) | 64.8±18.8 | 71.9±17.7 | 0.12 |
| SOFA score | 3.7±2.8 | 4.3±2.5 | 0.32 |
| APACHE II | |||
| Mean | 17.4±4.1 | 18.7±5.0 | 0.42 |
| ≥15 | 10 (71.4%) | 15 (78.9%) | 0.59 |
| Acute lung injury | |||
| Sepsis | 0 (0%) | 15.3% | 0.38 |
| Bacterial pneumonia | 6 (42.9%) | 6 (31.6%) | 0.50 |
| ICU ventilator data | |||
| TV (mL) | 415.9±128.7 | 511.0±79.9 | 0.02 |
| TV of IBW (mL/kg) | 6.8±1.9 | 9.4±1.4 | 0.01 |
| RR, breath/min | 23.3±5.5 | 19.7±6.4 | 0.05 |
| MV (L) | 9.0±2.7 | 9.3±2.3 | 0.89 |
| RSBI | 64.1±28.9 | 80.9±38.0 | 0.42 |
| Respiratory muscle strength | |||
| MIP (cmH2O) | 22.9±9.3 | 26.4±9.0 | 0.35 |
| MEP (cmH2O) | 25.5±14.3 | 26.9±18 | 0.73 |
| Nutrition | |||
| ALB (3.5–5 g/dL) | 2.6±9.3 | 2.7±9.3 | 0.68 |
Notes: Pearson chi-square test was used for sex, Student’s t-test was used for age, body weight, total ICU days, ventilator days before included, and nonparametric method for APACHE II and nutrition. Data is presented as either n(%) or mean ± SD.
Abbreviations: IBW, ideal body weight; PFT, pulmonary function test; TV, tidal volume; RR, respiratory rate; MV, minute volume; RSBI, rapid shallow breathing index; MIP, maximum inspiratory pressure; MEP, maximum expiratory pressure; NAVA, neutrally adjusted ventilatory assist; ICU, intensive care unit; FEV1/pred, predicted forced expiratory volume in 1 second; FEV1/FVC, forced expiratory volume in 1 second/forced vital capacity; APACHE II, Acute Physiology and Chronic Health Enquiry II; ALB, albumin; SOFA, Sequential Organ Failure Assessment.