Table 2.
Clinical data collection by T0, T1, T2a
| Variables | NAVA (n=14) | Conventional (n=19) | P-value | ||
|---|---|---|---|---|---|
| T0: data immediately post-Edi catheter insertion | |||||
| TV (mL) | 424.9 | ±102.4 | 448.9 | ±100.6 | 0.71 |
| TV of IBW (mL/kg) | 7.1 | ±1.9 | 8.3 | ±1.9 | 0.09 |
| RR, breath/min | 22.3 | ±5.2 | 22.8 | ±7.3 | 0.21 |
| MV (L) | 9.7 | ±2.1 | 9.4 | ±2.1 | 0.78 |
| TV/Edi (NVE) | 71.9 | ±41.9 | 92.9 | ±66.9 | 0.48 |
| RSBI | 64.1 | ±28.9 | 80.9 | ±38.0 | 0.42 |
| MIP (cmH2O) | 20.0 | ±1.0 | 20.5 | ±9.3 | 0.71 |
| MEP (cmH2O) | 14.0 | ±0.1 | 21.5 | ±10.6 | 0.46 |
| P0.1, cmH2O | 1.1 | ±1.0 | 1.0 | ±1.1 | 0.81 |
| PEEPi, cmH2O | 2.3 | ±3.4 | 3.9 | ±3.7 | 0.27 |
| ALB (3.5–5 g/dL) | 1.7 | ±1.5 | 2.4 | ±0.5 | 0.23 |
| T1: data after intervention | |||||
| Ventilator data | |||||
| TV (mL) | 435.7 | ±109.3 | 463.3 | ±104.3 | 0.42 |
| TV of IBW (mL/kg) | 7.2 | ±1.8 | 8.5 | ±1.8 | 0.05 |
| RR, breath/min | 26.0 | ±6.7 | 23.2 | ±8.7 | 0.23 |
| MV (L) | 10.5 | ±2.0 | 10.2 | ±3.2 | 0.68 |
| TV/Edi (NVE) | 74.7 | ±54.9 | 89.5 | ±70.1 | 0.71 |
| RSBI | 91.6 | ±57.9 | 127.1 | ±141.3 | 0.55 |
| MIP (cmH2O) | 25.4 | ±12.6 | 26.0 | ±14 | 0.96 |
| MEP (cmH2O) | 32.0 | ±20.2 | 26.1 | ±24 | 0.21 |
| P0.1, cmH2O | 1.2 | ±1.7 | 1.1 | ±0.9 | 0.84 |
| PEEPi, cmH2O | 2.4 | ±4.9 | 2.7 | ±3.6 | 0.77 |
| ALB (3.5–5 g/dL) | 1.7 | ±1.5 | 2.4 | ±0.5 | 0.51 |
| T2: data at the end of SBT trial | |||||
| TV (mL) | 373.8 | ±80.9 | 391.6 | ±87.7 | 0.67 |
| TV of IBW (mL/kg) | 6.1 | ±1.1 | 7.2 | ±1.6 | 0.05 |
| RR, breath/min | 24.7 | ±4.7 | 25.7 | ±8.7 | 0.87 |
| MV (L) | 8.9 | ±2.1 | 9.4 | ±2.3 | 0.51 |
| TV/Edi (NVE) | 54.0 | ±52.5 | 54.4 | ±49.9 | 0.86 |
| RSBI | 104.6 | ±54.2 | 129.6 | ±120.7 | 0.87 |
| MIP (cmH2O) | 30.9 | ±12.6 | 26.7 | ±11.1 | 0.42 |
| MEP (cmH2O) | 31.6 | ±17.8 | 25.9 | ±23.2 | 0.16 |
| ALB (3.5–5 g/dL) | 2.5 | ±0.7 | 3.0 | ±0.1 | 0.31 |
Notes:
a
Nonparametric method. Data presented as mean ± standard deviation.
Abbreviations: IBW, ideal body weight; NAVA, neutrally adjusted ventilatory assist; TV, tidal volume; RR, respiratory rate; MV, minute volume; RSBI, rapid shallow breathing index; MIP, maximum inspiratory pressure; MEP, maximum expiratory pressure; Edi, diaphragm electrical activity; NVE, tidal volume/neuro-ventilatory efficiency; PEEPi, intrinsic positive end-expiratory pressure; SBT, spontaneous breathing trial; ALB, albumin; p0.1, negative airway pressure generated during the first 100 msec of an occluded inspiration.