Table 2.
Change in macular pigment optical density and total macular pigment complement using the DWAF
Parameter | Baseline, mean (SD) | 3 months mean (SD) | Change in 0–3 months, mean (SD) | P-value | 6 months, mean (SD) | Change in 0–6 months, mean (SD) | P-value |
---|---|---|---|---|---|---|---|
Macular pigment optical density: n =49 | |||||||
DWAF optical density 0.5 with 7° reference | 0.31±0.25 | 0.39±0.26 | 0.081±0.26 | 0.31 | 0.39±0.27 | 0.082±0.274 | 0.041 |
Macular pigment volume: n =49 | |||||||
DWAF volume with 10.5° reference | 3,466.7±3,179.3 | 5,048.5±3,376.6 | 1,581.8±3,627.1 | 0.004 | 5,791.1±4,110.0 | 2,324.3±4,134.1 | ,0.001 |
Notes: Results are in response to an analysis of variance; significant P-values are those <0.05.
Abbreviation: DWAF, dual-wavelength autofluorescence.