Table S1.
Partial correlation of WMH parameter and extracted GM density values in abnormal regions identified by VBM analysis (ρ/P-values)
| Lesion volume | Lesion fraction | WMH scores | |
|---|---|---|---|
| lMFG | −0.642/0.002* | −0.629/0.002* | −0.236/0.303 |
| bACC | −0.435/0.049** | −0.507/0.019** | −0.036/0.878 |
| lPMC | −0.205/0.372 | −0.264/0.247 | −0.075/0.747 |
| lMCC | −0.416/0.061 | −0.425/0.055 | −0.042/0.857 |
| rMCC | −0.480/0.028** | −0.484/0.026** | −0.122/0.600 |
| rPMC | −0.385/0.085 | −0.438/0.047** | −0.051/0.825 |
| bCAL | −0.338/0.134 | −0.365/0.104 | −0.136/0.557 |
| lMTG | 0.187/0.405 | 0.145/0.520 | 0.417/0.053 |
| rTPJ | −0.453/0.039** | −0.484/0.026** | −0.101/0.663 |
| lPFC | −0.467/0.033** | −0.469/0.032** | −0.285/0.210 |
| rPFC | −0.385/0.085 | −0.438/0.047** | −0.051/0.825 |
| lIPL | −0.124/0.593 | −0.158/0.493 | 0.117/0.614 |
Notes:
*
P<0.01.
**
P<0.05.
Abbreviations: WMH, white matter hyperintense; GM, gray matter; VBM, voxel-based morphometry; l, left; MFG, middle frontal gyrus; b, bilateral; ACC, anterior cingulate cortex; PMC, premotor cortex; MCC, middle cingulate cortex; r, right; CAL, cerebellum anterior lobe; MTG, middle temporal gyrus; TPJ, temporoparietal junction; PFC, prefrontal cortex; IPL, inferior parietal lobule.