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. 2016 May 10;11:999–1004. doi: 10.2147/COPD.S108505

Table 4.

Six-month follow-up of adults tested for AATD according to AAT levels

Diagnosis after AAT determination Normal AAT levels (n=10,445) Intermediate deficiency (n=607) Severe deficiency (n=22)
COPD 106 (1) 5 (0.8) 2 (9.1)*
Emphysema 36 (0.3) 1 (0.2) 2 (9.1)**
Chronic bronchitis 18 (0.2) 2 (0.3) 0
Respiratory infections 3,090 (29.5) 148 (24.4)** 10 (45.5)*
Pneumonia 58 (0.6) 3 (0.5) 0
Spirometry 407 (2.9) 24 (4) 2 (9.1)
Referrals
Pneumology 229 (2.2) 22 (3.6)* 3 (13.6)*
Gastroenterology 489 (4.7) 42 (6.9)* 0
Internal medicine 73 (0.7) 2 (0.3) 1 (4.5)

Notes:

*

P<0.05 and

**

P<0.01 compared to individuals with normal levels of AAT. Data are expressed as n (%).

Abbreviations: AAT, alpha-1 antitrypsin; AATD, alpha-1 antitrypsin deficiency.