Table 4.
Six-month follow-up of adults tested for AATD according to AAT levels
| Diagnosis after AAT determination | Normal AAT levels (n=10,445) | Intermediate deficiency (n=607) | Severe deficiency (n=22) |
|---|---|---|---|
| COPD | 106 (1) | 5 (0.8) | 2 (9.1)* |
| Emphysema | 36 (0.3) | 1 (0.2) | 2 (9.1)** |
| Chronic bronchitis | 18 (0.2) | 2 (0.3) | 0 |
| Respiratory infections | 3,090 (29.5) | 148 (24.4)** | 10 (45.5)* |
| Pneumonia | 58 (0.6) | 3 (0.5) | 0 |
| Spirometry | 407 (2.9) | 24 (4) | 2 (9.1) |
| Referrals | |||
| Pneumology | 229 (2.2) | 22 (3.6)* | 3 (13.6)* |
| Gastroenterology | 489 (4.7) | 42 (6.9)* | 0 |
| Internal medicine | 73 (0.7) | 2 (0.3) | 1 (4.5) |
Notes:
P<0.05 and
P<0.01 compared to individuals with normal levels of AAT. Data are expressed as n (%).
Abbreviations: AAT, alpha-1 antitrypsin; AATD, alpha-1 antitrypsin deficiency.