Table 2.
Patient and joint characteristics of the series of X-rays scored without the consensus atlas and the series of X-rays scored with the consensus atlas
| Series without consensus atlas (10 patients, 120 joints) | Series with consensus atlas (10 patients, 120 joints) | p value | |
|---|---|---|---|
| Age (years) | 35.8 (27.7–47.5) | 33.7 (28.8–43.4) | 0.97 |
| Type of haemophilia (A / B) | 90 % / 10 % | 80 % / 20 % | 1.00 |
| Severity (moderate / severe) a | 20 % / 80 % | 20 % / 80 % | 1.00 |
| Treatment (on demand / prophylactic) | 40 % / 60 % | 10 % / 90 % | 0.30 |
| Joints with surgery | 1.7 % | 3.3 % | 1.00 |
| Pettersson score at joint level | |||
| Percentage abnormal scores | 64 % | 49 % | 0.28 b |
| Median of all scores | 3 (0–7) | 0 (0–4) | 0.45 b |
| Median of abnormal scores only | 6 (3–9) | 4 (2–9) | 0.67 b |
| Pettersson score at patient level | |||
| Percentage abnormal scores | 90 % | 85 % | 0.73 b |
| Median of all scores | 25 (10–36) | 9 (2–23) | 0.28 b |
| Median of abnormal scores only | 26 (19–37) | 12 (7–24) | 0.24 b |
Values are percentages and medians (inter quartile ranges) regarding the average score of the three observers
a Severity of disease according to true serum levels of coagulation factors VIII in haemophilia A or IX in haemophilia B
b Calculated using regression analyses adjusted for repeated measurements and clustering of joints within patients