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. 2015 May 15;26(6):2612–2625. doi: 10.1093/cercor/bhv099

Figure 3.

Figure 3.

Thalamocortical innervation of A1 inhibitory neurons. (A) Fluorescence image of labeled PV neurons in the A1 of a PV-Cre;Ai14 mouse. (B) Fluorescence image of an A1 slice from a SOM-Cre;Ai14 mouse. (C) Image of an A1 slice from a VIP-Cre;Ai14 mouse. (D) Top, reconstructed morphologies (dark for dendrites, gray for axons) of 3 recorded PV neurons. Scale: 50 µm. Bottom, sample membrane potential/spike responses of a PV cell to current injections at 2 different levels. Scale: 50 pA and 50 ms. (E) Morphology and intrinsic spiking property for SOM neurons. (F) Morphology and intrinsic spiking property for VIP neurons. (G) Monosynaptic EPSCs recorded in sample PV cells in different layers of the same slice. Two example slices are shown. (H) EPSCs of example SOM neurons. (I) EPSCs of example VIP neurons. (J) Plot of threshold intensity of current injections that produce spikes vs. spike width for 4 types of neuron. Spike width was measured at the half-peak level above the spike threshold. (K) Fluorescence image of an A1 slice from a GAD1-GFP mouse. (L) EPSCs of example L1 inhibitory neurons recorded in 2 slices.