Extended Data Figure 10. A schematic representation of interchromosomal LAIR-1 transposition.

Shown is the insertion of a fragment of LAIR-1 into the Ig heavy chain locus through a mechanism still to be molecularly defined, followed by the acquisition of somatic mutations that increase binding to IE and abolish binding to collagen.

NIHMS66054-supplement-ExDatFig10.pdf ^{(1.7MB, pdf)}