. 2016 May 17;77(3):393–404. doi: 10.15288/jsad.2016.77.393

Table 1.

Tested alcohol dehydrogenase (ADH) gene variants

Marker	Chromosomal position^a	Gene	Functionality/placement	Alleles^b	Minor allele frequency^c	Genotype frequency^b (n)
Marker	Chromosomal position^a	Gene	Functionality/placement	Alleles^b	Minor allele frequency^c	Homozygous for minor allele	Homozygous	Heterozygous for major allele
rs1229984	100239319	AHD1B	missense	G:A	0.031	18	449	7,204
rs2066702	100229017	ADH1B	missense	C:T	0.038	36	457	7,183
rs698	100260789	ADH1C	missense	A:G	0.345	978	3,313	3,360
rs1042364	100045574	ADH4	3'-UTR	G:A	0.247	519	2,778	4,371
rs1800759	100065509	ADH4	5' promoter	C:A	0.487	1,928	3,452	2,272

Notes: UTR = Untranslated region.

^{^a}

Positions reference human genome assembly GRCh37.p13;

^{^b}

alleles are listed as major:minor allele with the high-risk allele (based on past studies) in bold;

^{^c}

minor allele and genotype frequencies are for the combined sample. Markers with significant interaction effects (p < .05) are in bold.