Table 1.
Baseline characteristics
| All (n = 26) | PAH (n = 18) | CTEPH (n = 8) | P | |
|---|---|---|---|---|
| Age, years | 55 ± 10 | 55 ± 7 | 55 ± 6 | 0.89 |
| Male, no. (%) | 5 (19) | 4 (22) | 1 (13) | 0.50 |
| BMI | 24.07 ± 6.71 | 24.19 ± 8.02 | 23.84 ± 3.04 | 0.87 |
| WHO-FC II/III/IV, no. | 3/17/6 | 2/12/4 | 1/5/2 | 0.97 |
| I/CHD/porto/CTD, no. | 8/2/2/6 | 8/2/2/6 | … | … |
| Laboratory | ||||
| BNP, median (range), pg/mL | 273 (85–310) | 344 (98–546) | 115 (26–134) | 0.02 |
| Uric acid, mg/dL | 6.8 ± 2.1 | 7.0 ± 2.2 | 6.2± 1.9 | 0.37 |
| Cardiac catheterization | ||||
| PAWP, mmHg | 9.9 ± 3.8 | 10.2 ± 4.0 | 9.1 ± 3.3 | 0.46 |
| Systolic PAP, mmHg | 77 ± 21 | 75 ± 23 | 80 ± 14 | 0.52 |
| Diastolic PAP, mmHg | 29 ± 10 | 30 ± 10 | 26 ± 8 | 0.33 |
| Mean PAP, mmHg | 47 ± 12 | 47 ± 14 | 47 ± 8 | 0.92 |
| PVR, Wood units | 10.15 ± 6.61 | 10.94 ± 7.68 | 8.37 ± 2.78 | 0.23 |
| RAP, mmHg | 7.12 ± 4.07 | 7.11 ± 4.51 | 7.13 ± 3.14 | 0.99 |
| Svo2, % | 62.7 ± 8.4 | 63.5 ± 9.0 | 60.9 ± 6.9 | 0.43 |
| Cardiac output, L/min | 4.46 ± 1.70 | 4.34 ± 1.92 | 4.69 ± 1.31 | 0.60 |
| Cardiac index, L/min/m2) | 2.76 ± 0.90 | 2.72 ± 0.96 | 2.86 ± 0.86 | 0.71 |
Note
Unless otherwise noted, data are mean ± SD. BMI: body mass index; BNP: brain natriuretic peptide; CTEPH: chronic thromboembolic pulmonary hypertension; I/CHD/porto/CTD: idiopathic PAH/PAH with congenital heart disease/portopulmonary PAH/PAH with collagen tissue disease; PAH: pulmonary arterial hypertension; PAP: pulmonary arterial pressure; PAWP: pulmonary artery wedge pressure; PVR: pulmonary vascular resistance; RAP: right atrial pressure; Svo2: mixed venous oxygen saturation; WHO-FC: Word Health Organization functional class.