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. 2016 Jun;6(2):181–190. doi: 10.1086/686020

Table 1.

Patients demographics, right heart catheterization (RHC) data, and mathematical model–image-derived parameters

No PH PH
Median Mean ± SD IQR Median Mean ± SD IQR P
Demographics
 Patients, no. 15 57
 Male/female sex, no. 7/8 25/32
 Age, years 59 56 ± 16 29 67 64 ± 16 23 0.084
RHC data
 mPAP, mmHg 22 21 ± 3 2.75 45 44.7 ± 14.3 16.5 <0.001
 PVR, Wood units 2 1.9 ± 0.7 1.28 6 6.9 ± 4.5 5.39 <0.001
 mRAP, mmHg 5 4.9 ± 2.4 4 10 11.3 ± 3.1 7.5 <0.001
 CO, L/min 7 6.5 ± 1.4 2.42 5 5.2 ± 1.5 1.9 0.005
1D model–derived parameter
 Wb/Wtot 0.26 0.26 ± 0.1 0.12 0.42 0.4 ± 0.1 0.12 <0.001
0D model–derived parameters
 Rd, mmHg s/mL 0.3 0.36 ± 0.24 0.23 0.59 0.87 ± 0.73 0.53 <0.001
 Rc, mmHg s/mL 0.038 0.037 ± 0.013 0.07 0.003 0.051 ± 0.13 0.05 0.05
 C, mL/mmHg 1.29 4.74 ± 12.9 0.91 0.69 0.73 ± 0.4 0.43 <0.001
PA imaging–derived parameters
 RAC, % 26.2 25.9 ± 12.52 16.84 13.9 14.6 ± 7.41 11.74 <0.001
CMR
 RVEDVI, mL/m2 72.8 69.9 ± 21.9 40.54 78 87.6 ± 34.2 43.31 0.095
 RVEF, % 50.3 51.4 ± 8.86 9.78 41 40.3 ± 13.5 18.6 0.004
 VMI, ratio 0.23 0.28 ± 0.15 0.1 0.37 0.45 ± 0.27 0.29 0.006
 RVMI, g/m2 10.3 12.1 ± 3.95 6.87 20.1 21.6 ± 11.2 14.14 <0.001
 Systolic septal angle, degrees 142 144 ± 10.3 15 168 168 ± 22.3 32.25 <0.001
Note

PH: pulmonary hypertension; SD: standard deviation; IQR: interquartile range; mPAP: mean pulmonary arterial pressure measured at RHC; PVR: pulmonary vascular resistance measured at RHC; mRAP: mean right atrium pressure measured at RHC; CO: cardiac output, measured using thermodilution; Wb/Wtot: ratio of backward to total wave power computed from one-dimensional (1D) model; Rd: distal resistance computed from Windkessel (zero-dimensional [0D]) model; Rc: characteristic resistance computed from Windkessel model; C: total pulmonary compliance computed from Windkessel model; RAC: relative area change calculated from two-dimensional images of main pulmonary artery (PA); RVEDVI: right ventricle end-diastolic volume index calculated from cardiac magnetic resonance (CMR) images; RVEF: right ventricle ejection fraction calculated from CMR images; VMI: ventricular mass index calculated from CMR images; RVMI: right ventricle mass index calculated from CMR images.