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. Author manuscript; available in PMC: 2016 May 17.
Published in final edited form as: Gut. 2014 Dec 10;65(1):100–111. doi: 10.1136/gutjnl-2014-308043

Figure 5.

Figure 5

Interleukin (IL)-1β+keratinocyte chemoattractant (KC)/growth-regulated oncogene (GRO) and triolein coadministration results in worse local and systemic inflammation during caerulein (CER) pancreatitis. Immunohistochemistry images for myeloperoxidase (MPO) in the pancreas (A1–5) and lungs (B1–5), with each group mentioned at the bottom of the image. While caerulein pancreatitis increased MPO-positive cells compared with controls (A2, A6*), IL-1β+KC/GRO coadministration caused a further increase (A3, A6 †), compared with caerulein alone. Systemically, in the lungs, IL-1β+KC/GRO coadministration (B3) and triolein coadministration (B4) significantly increased MPO-positive cells compared with caerulein pancreatitis alone (B2) or other groups (B1,4,5). Orlistat treatment significantly reduced (B6, †) the lung MPO increased noted in the CER+ triolein group.