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. Author manuscript; available in PMC: 2016 May 17.
Published in final edited form as: J Clin Immunol. 2014 Sep 23;34(8):971–978. doi: 10.1007/s10875-014-0099-z

Table 1. Correlations between determined serum cytokine levels and the expression of activation markers (HLA-DR and CD45R0) on peripheral blood CD4+ and CD8+ lymphocytes of CVID patients.

No significant correlations were observed for IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-7, IL-8, IL-9, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17, IFNα2, GM-CSF, TNFβ, TGFα, sCD40-L, VEGF, CCL-3/MIP-1α, CCL-4/MIP-1β, CCL-22/MDC, CCL-2/MCP-1, CCL-7/MCP-3, GRO, fractalkine, EGF, EGF-2, and CCL-11/eotaxin. Spearman rank order correlation was used for the analysis, Spearman coefficient R is indicated; results with p<0.05 are in bold letters.

CD4+HLA-DR+/CD4+ CD8+HLA-DR+/CD8+ CD4+CD45RO+/CD4+ CD8+CD45RO+/CD8+
R p R p R p R p
Flt3Ligand 0.38 0.02 0.27 0.11 0.45 0.01 0.01 0.94
G-CSF 0.37 0.03 0.26 0.13 0.42 0.01 0.25 0.15
IFNγ 0.21 0.23 0.35 0.04 0.09 0.58 −0.01 0.97
IL-1RA 0.35 0.04 0.26 0.14 0.20 0.24 0.39 0.02
IL-5 0.33 0.05 0.35 0.04 0.23 0.18 −0.07 0.67
IL-6 0.37 0.03 0.37 0.03 0.34 0.05 0.13 0.45
IL-10 0.37 0.03 0.06 0.72 0.44 0.01 0.06 0.74
IP-10 0.60 <0.01 0.42 0.02 0.51 <0.01 0.36 0.04
sCD25 0.35 0.04 0.19 0.28 0.20 0.25 0.37 0.03
TNFα 0.39 0.02 0.40 0.02 0.29 0.09 −0.01 0.96