Table 2. Cohort description.
Patients (n = 212) | ||
---|---|---|
Demographics | ||
Age (median, range) | 60 | 18–93 |
Male (n,%) | 106 | 50 |
History of previous seizures (n,%) | 104 | 49.1 |
Center (n,%) | ||
CHUV | 104 | 49.1 |
BWH | 65 | 30.7 |
MGH | 30 | 14.2 |
BIDMC | 13 | 6.1 |
SE characteristics | ||
Worst seizure type (n,%) | ||
Focal without consciousness impairment | 32 | 15.1 |
Focal with consciousness impairment | 57 | 28.9 |
Absence | 3 | 1.42 |
Myoclonic | 1 | 0.5 |
Generalized convulsive | 102 | 48.1 |
Nonconvulsive SE in coma | 17 | 8 |
Level of consciousness before treatment (n,%) | ||
Alert | 24 | 11.3 |
Confused | 51 | 24.1 |
Somnolent | 13 | 6.1 |
Stuporous | 88 | 41.5 |
Comatose | 36 | 17 |
STESS (mean, SD) | 2.64 | 1.63 |
Refractory SE (n,%) | 119 | 56.12 |
Number of different ASD used (median, range) | 3 | 0–13 |
Coma induction for SE control (n,%) | 24 | 11.3 |
Outcome at discharge (n,%) | ||
Return to clinical premorbid baseline | 96 | 45.3 |
New morbidity | 89 | 42 |
Death | 27 | 12.8 |
ASD, antiseizure drug; BWH, Brigham and Women’s Hospital; BIDMC, Beth Israel Deaconess Medical Center; CHUV, Lausanne University Hospital; MGH, Massachusetts General Hospital; STESS, Status Epilepticus Severity Score.