Table 1.

17 Guideline indicator definitions and coding scheme for indicators for intensive care unit (ICU) management of adults with severe traumatic brain injury.

Guideline Indicators**	Definitions and coding
Hypoxia treated in 30 minutes after onset Condition = Hypoxia	0 = Hypoxic and not treated with O2 0 = Hypoxic and treated with O2 >30 minutes 1 = Hypoxic but treated with O2 ≤ 30 minutes 2 = No hypoxia (All SaO2 ≥ 90% or PaO2 ≥ 60mmHg)
Hypotension treated within 30 minutes after onset Condition = Hypotension	0 = Hypotension and not treated 0 = Hypotension and treated > 30 minutes after hypotension onset 1 = Hypotension and treated in ≤ 30 minutes 2 = No hypotension (All SBP ≥ 90mmHg)
ICP monitor used	0 = ICP monitor not used 1 = ICP monitor used
All CPP between 50–70 mmHg Condition = ICP monitored	0 = All CPP not between 50–70 mmHg 1 = All CPP between 50–70 mmHg 2 = ICP not monitored
Any treatment given for high ICP Condition = High ICP*	0 = Any treatment not given for high ICP 1 = Any treatment given for high ICP 2 = No high ICP
Mannitol used for treatment of high ICP Condition = High ICP*	0 = Mannitol is not used to treat high ICP 1 = Mannitol used to treat high ICP 2 = No high ICP
Propofol used for treatment of high ICP Condition = High ICP*	0 = Propofol not used to treat high ICP 1 = Propofol used to treat high ICP 2 = No high ICP
Prophylactic hyperventilation¥ is not used for treatment of high ICP Condition = High ICP*	0 = Prophylactic hyperventilation is used to treat high ICP 1 = Prophylactic hyperventilation is not used to treat high ICP 2 = No high ICP
Target temperatures± maintained for 48 hours (prophylactic hypothermia not used)	0 = Target temperatures not maintained 1 = Target temperatures maintained
Pre-intubation antibiotics used	0 = Pre-intubation antibiotics not used 1 = Pre-intubation antibiotics used
Early tracheostomyo performed	0 = Early tracheostomy not performed 1 = Early tracheostomy performed
Deep Vein Thrombosis (DVT) prophylaxis used (Low molecular weight heparin or compression device)	0 = DVT prophylaxis not used 1 = DVT prophylaxis used
Treatment thresholds of SJO2 ≥ 50% or PbrO2 ≥15 mmHg used Condition = SJO2 or PbrO2 monitored	0 = Treatment thresholds of SJO2<50% or PbrO2<15 mmHg used 1 = Treatment thresholds of SJO2≥50% or PbrO2≥15 mmHg used 2 = SJO2 or PbrO2 not monitored.
Prophylactic barbiturate coma not induced	0 = Prophylactic barbiturate coma induced 1 = Prophylactic barbiturate coma not induced
Prophylactic antiepileptic drugs used to prevent early seizures	0 = No prophylactic antiepileptic drugs used 1 = Prophylactic antiepileptic drugs used
Nutrition$ started within 72 hours	0 = Nutrition not started 0 = Nutrition start >72 hours after ICU admission 1 = Nutrition start ≤ 72 hours after ICU admission
No steroids used	0 = Steroids used 1 = Steroids not used

Coding: Yes=1, No=0, NA=2; Total possible adherence score in ICU. = 17 [range 0–17]

^**based on 2007 BTF Guidelines, NA = Not applicable

^*High ICP defined as ICP>20mmHg if an ICP monitor is in place or clinical signs of high ICP (unequal pupils and/or hypertension with bradycardia or radiographic evidence of progression of TBI.

^†PaCO₂ ≤ 25 mmHg

^‡Target temperature is defined as temperature between 35–38.5°C.

^§Early Tracheostomy is defined as Tracheostomy within 48 hours to admission to Trauma center.

^||Nutrition includes enteral, parenteral or combined