Table 1.
Demographics and Outcomes of GBM Metastases to the Vertebral Column
| Total No. Patients with Spine Metastases | Glioblastoma (N = 28) |
|---|---|
| Sex, male, n (%) | 19 (67.9) |
| Age at primary, years (range) | 38.4 (11–63) |
| Mean time to spine metastasis, months (range)* | 26.4 (4–90) |
| Location, n (%) | |
| Cervical | 3 (10.7) |
| Thoracic | 9 (32.1) |
| Lumbar | 5 (17.9) |
| Multilevel | 8 (28.6) |
| Unknown | 3 (10.7) |
| Treatment of primary GBM, n (%) | |
| Surgery alone | 5 (17.9) |
| Radiotherapy and/or chemotherapy | 1 (3.6) |
| Surgery and adjuvant therapy | 18 (64.2) |
| No treatment/unknown | 4 (14.3) |
| Treatment of spinal metastasis, n (%) | |
| Surgery alone | 0 (0) |
| Radiotherapy and/or chemotherapy | 3 (10.7) |
| Surgery and adjuvant therapy | 9 (32.1) |
| No treatment/unknown | 16 (57.1) |
| Survival, n (%) | |
| Patients with known survival | 25 (89.3) |
| Patients with unknown survival | 3 (10.7) |
| <3 months survival | 1 (4) |
| 3–11 months survival | 6 (24) |
| 12–23 months survival | 11 (44) |
| 24–60 months survival | 4 (16) |
| >60 months survival | 3 (12) |
| Overall mean survival from spine metastasis diagnosis, months, (range) | 10 (25 days–48 months) |
All percentages based off of a total # of patients (n), except for survival where percentages are based off of patients with known survival
GBM, glioblastoma multiforme.
*
Time to spine metastasis was not reported in 18 studies.