Table 2. Adverse Events (N=88).
Adverse Event | All Grades | Grade I | Grade 2 | Grade 3 |
---|---|---|---|---|
Fatigue | 51 (58%) | 31 (35%) | 18 (21%) | 2 (2%) |
Diarrhea | 34 (39%) | 24 (27%) | 9 (10%) | 1 (1%) |
HTN exacerbation | 38 (43%) | 24 (27%) | 12 (14%) | 2 (2%) |
Anorexia/ Weight loss | 24 (27%) | 15 (17%) | 8 (9%) | 1 (1%) |
Nausea/Vomiting | 21 (24%) | 13 (15%) | 8 (9%) | - |
Increased LFTs | 17 (19%) | 2 (2%) | 3 (3%) | 12 (14%) |
Hair and skin changes | 12 (14%) | 5 (6%) | 7 (8%) | - |
Myalgias/Arthragias | 9 (10%) | 7 (8%) | 2 (2%) | - |
Abdominal pain | 7 (8%) | 4 (5%) | 2 (2%) | 1 (1%) |
New-onset HTN | 5 (6%) | 1 (1%) | 4 (5%) | - |
Hypothyroidism | 5 (6%) | - | 5 (6%) | - |
There were no Grade 4 adverse events.
HTN, hypertension; LFTs, liver function tests