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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Adv Drug Deliv Rev. 2015 Nov 17;102:73–82. doi: 10.1016/j.addr.2015.11.012

Table 1.

Adjuvant systems in TB clinical trials

Adjuvant Vaccine antigen Delivery Immunomodulator Signalling pathwaya
GLA-SE ID93 Emulsion GLA; glucopyranosyl lipid
adjuvant		 TLR4
AS01 M72 Liposomes MPL; 3-O-desacyl-4’-
monophosphoryl lipid A		 TLR4
IC31® H4/H56 Polypeptide ODN1a;
oligodeoxynucleotide		 TLR9
CAF01 H1 Liposomes TDB; a synthetic variant of
mycobacterial cord factor		 Mincle;
a

Signalling pathway of the immunomodulator