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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Anesthesiology. 2016 Jun;124(6):1311–1327. doi: 10.1097/ALN.0000000000001111

Figure 9. Anesthesia down-regulates expression of c-Fos and brain-derived neurotrophic factor (BDNF) protein in the immature hippocampus.

Figure 9

We used Western blotting to assess the protein levels of c-Fos (A and B) and BDNF (C and D). Anesthesia caused a decrease in expression of c-Fos when measured at 2 h (A; *, p=0.02; n=6) and at 24 h (B; *, p=0.015; n=7) as compared with age-matched controls. Anesthesia causes a decrease in BDNF protein when measured at 2 h (C; ***, p=0.0002; n=14) and at 24 h (D; **, p=0.0016; n=14), as compared with aged-matched sham controls.