Table 1.
Treatment of β-elemene could reverse the imbalance of Treg/Th17 in the mouse spleen induced by rapamycin (mean ± SD, n = 6).
| Group | ||||
|---|---|---|---|---|
| Control | Rapamycin 5 mg/kg |
β-elemene 50 mg/kg |
Rapamycin 5 mg/kg + β-elemene 50 mg/kg | |
| Treg/Th17 | 2.2 ± 0.2 | 5.8 ± 0.6# | 1.1 ± 0.3# | 3.4 ± 1.1∗ |
| Treg/CD4+ (%) | 7.6 ± 0.8 | 12.2 ± 1.3# | 4.7 ± 0.7# | 10.1 ± 2.8∗ |
| Th17/CD4+ (%) | 3.6 ± 0.4 | 2.1 ± 0.2# | 4.4 ± 1.3 | 2.8 ± 0.9 |
| CD4+ T (%) | 25.4 ± 3.1 | 22.9 ± 4.3 | 27.7 ± 4.5 | 26.6 ± 5.3 |
# p < 0.05 versus control group; ∗ p < 0.05 versus rapamycin group.