Table 3.
The effects of CM and Met on the levels of Scr, BUN, and albuminuria in serum and NAG in urine of diabetic rats.
| Scr (μmol/L) | BUN (mmol/L) | Albuminuria (mg/mL) | NAG (U/L) | ||
|---|---|---|---|---|---|
| CTRL | — | 143.8 ± 31.3 | 5.1 ± 0.5 | 0.9 ± 0.05 | 30.2 ± 6.4 |
| Model | — | 338.8 ± 32.3## | 10.2 ± 0.7## | 2.6 ± 0.3## | 75.7 ± 7.7## |
| CM (g/kg) | 0.5 | 328.4 ± 22.2## | 9.2 ± 1.0## | 2.0 ± 0.3## | 60.8 ± 7.5## |
| 1.0 | 228.5 ± 54.6#∗∗ | 8.2 ± 0.5##∗ | 1.8 ± 0.2##∗ | 68.9 ± 8.1## | |
| 2.0 | 226.3 ± 32.1#∗∗ | 8.6 ± 1.2## | 1.9 ± 0.3## | 73.2 ± 9.0## | |
| Met (mg/kg) | 100 | 288.5 ± 74.9## | 9.3 ± 1.1## | 2.0 ± 0.3## | 62.9 ± 9.1## |
Data are expressed as mean ± SEM (n = 6) and analyzed using one-way ANOVA. # P < 0.05 and ## P < 0.01 versus normal controls. ∗ P < 0.05 and ∗∗ P < 0.01 versus model group.