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. 2016 May 17;353:i2351. doi: 10.1136/bmj.i2351

Table 2.

Pooled hazard ratios (95% CI) for incident hypertension for total consumption of potatoes (baked, boiled, or mashed potatoes and French fries) in Nurses’ Health Study, Nurses’ Health Study II, and Health Professional Follow-up Study

Consumption levels Linear P for trend P for heterogeneity
≤1 per month 1-3 per month 1-3 per week 4-6 per week ≥1 per day
Nurses’ Health Study
Cases/person years 291/10 480 4527/143 881 18 286/516 243 12 085/344 911 539/18 743
Multivariate adjusted HR† 1.00 (reference) 1.00 (0.89 to 1.13) 1.05 (0.93 to 1.18) 1.09 (0.97 to 1.23) 1.07 (0.92 to 1.24) <0.001
Nurses’ Health Study II
Cases/person years 156/13 108 2065/127 696 13 635/752 459 8947/430 729 443/20 484
Multivariate adjusted HR† 1.00 1.04 (0.88 to 1.22) 1.13 (0.96 to 1.32) 1.23 (1.04 to 1.44) 1.42 (1.18 to 1.72) <0.001
Health Professionals Follow-up Study
Cases/person years 156/6004 1918/67 267 7958/261 776 6304/209 045 416/16 138
Multivariate adjusted HR† 1.00 0.96 (0.81 to 1.13) 0.99 (0.84 to 1.16) 1.01 (0.86 to 1.19) 0.96 (0.79 to 1.16) 0.20
Pooled results
HR with random effect model 1.00 1.00 (0.92 to 1.09) 1.05 (0.97 to 1.14) 1.11 (1.02 to 1.22) 1.13 (0.91 to 1.40) 0.02 <0.001
HR with fixed effect model 1.00 1.00 (0.92 to 1.09) 1.05 (0.97 to 1.14) 1.10 (1.02 to 1.20) 1.12 (1.02 to 1.24) <0.001

*Follow-up from 1984 to 2012.

†Hazard ration adjusted for age, race/ethnicity (white, African-American, Asian, Hispanic, other), body mass index, current smoking status, physical activity, weight change per food frequency questionnaire cycle, menopausal status (in NHS and NHS II), alcohol intake, current oral contraceptive use (in NHS II), analgesic use (non-steroidal anti-inflammatory drugs, acetaminophen (paracetamol), aspirin), family history of hypertension, total energy intake, animal flesh intake (combination of processed and unprocessed red meat, poultry, and seafood), whole grains (fifths), sugar sweetened drink intake, artificially sweetened diet drink intake, total fruit, total vegetables.

‡Follow-up from 1991 to 2011.

§Follow-up from 1986 to 2012.