Table 3.
Pooled hazard ratios (95% CI) for incident hypertension for consumption of potatoes (baked, boiled, or mashed) in Nurses’ Health Study, Nurses’ Health Study II, and Health Professional Follow-up Study
Consumption levels | P for trend | P for heterogeneity |
||||
---|---|---|---|---|---|---|
≤1 per month | 1-3 per month | 1-3 per week | ≥4 per week | |||
NHS | ||||||
Cases/person years | 406/14 882 | 6233/189 737 | 22 353/648 475 | 6736/181 163 | ||
Multivariate adjusted HR† | 1.00 (reference) | 1.07 (0.97 to 1.19) | 1.12 (1.01 to 1.24) | 1.13 (1.02 to 1.26) | 0.01 | |
NHS II | ||||||
Cases/person years | 333/25,721 | 5673/327 099 | 16 338/867 668 | 2902/123 987 | ||
Multivariate adjusted HR† | 1.00 | 1.08 (0.97 to 1.21) | 1.17 (1.04 to 1.31) | 1.25 (1.11 to 1.41) | <0.001 | |
HPFS | ||||||
Cases/person years | 308/11 050 | 3088/102 773 | 10 668/361 971 | 2688/84 435 | ||
Multivariate adjusted HR† | 1.00 | 0.92 (0.82 to 1.04) | 0.95 (0.84 to 1.07) | 0.95 (0.84 to 1.08) | 0.46 | |
Pooled results | ||||||
HR with random effect model | 1.00 | 1.03 (0.93 to 1.13) | 1.08 (0.96 to 1.21) | 1.11 (0.96 to 1.28) | 0.05 | 0.002 |
HR with fixed effect model | 1.00 | 1.03 (0.97 to 1.10) | 1.08 (1.02 to 1.15) | 1.11 (1.04 to 1.19) | <0.001 |
*Follow-up from 1984 to 2012.
†Hazard ration adjusted for age, race/ethnicity (white, African-American, Asian, Hispanic, other), body mass index, current smoking status, physical activity, weight change per food frequency questionnaire cycle, menopausal status (in NHS and NHS II), alcohol intake, current oral contraceptive use (in NHS II), analgesic use (non-steroidal anti-inflammatory drugs, acetaminophen (paracetamol), aspirin), family history of hypertension, total energy intake, animal flesh intake (combination of processed and unprocessed red meat, poultry, and seafood), whole grains (fifths), sugar sweetened drink intake, artificially sweetened diet drink intake, total fruit, total vegetables.
‡Follow-up from 1991 to 2011.
§Follow-up from 1986 to 2012.