Table 2.
Comparison between patients who obtained a clinical pregnancy (n = 75; 75 cycles) and those who did not (n = 235; 308 cycles)
| Clinical pregnancy | No pregnancy | p | |
|---|---|---|---|
| Age (years) | 37 ± 3.2 | 38.3 ± 3.6 | <0.0005 |
| AMH (ng/ml) | 0.3 ± 0.2 | 0.3 ± 0.2 | ns |
| BMI (kg/m2) | 22.4 ± 3.6 | 23.0 ± 3.3 | ns |
| AFC | 7.4 ± 3.1 | 6.3 ± 3.2 | <0.003 |
| Basal FSH (IU/l) | 10.6 ± 3.4 | 10.5 ± 4.5 | ns |
| Concause of infertility | |||
| Male | 33 (44.0 %) | 114 (37.0 %) | ns |
| Tubal | 6 (8.0 %) | 30 (9.7 %) | |
| Mixed | 17 (22.7 %) | 37 (15.7 %) | |
| Ovarian endometriosisa | 19 (25.3 %) | 54 (17.5 %) | ns |
| COS protocol | |||
| GnRH agonist “long” | 45 (60 %) | 149 (48.4 %) | ns |
| GnRH antagonist | 30 (40 %) | 265 (51.6 %) | |
| Medications | |||
| Recombinant Gn | 24 (32 %) | 108 (35.1 %) | ns |
| hMG | 51 (68.0 %) | 200 (64.9 %) | |
| Total gonadotropin dose (IU) | 3155 ± 1370 | 2844 ± 1380 | ns |
| Retrieved COCs | 4.5 ± 2.8 | 3.2 ± 2.8 | <0.0001 |
| Mature (MII) oocytes | 3.9 ± 2.5 | 2.6 ± 2.3 | <0.0001 |
| Motile sperm (millions) | 14 ± 21.2 | 18 ± 26.9 | ns |
| Fertilized oocytes | 2.8 ± 1.8 | 1.8 ± 1.7 | <0.0001 |
| Fertilization rate (%) | 77.5 | 68.3 | <0.005 |
| Available embryos | 2.7 ± 1.6 | 1.6 ± 1.5 | <0.0001 |
| Mean embryo score | 7.8 ± 1.8 | 7.7 ± 1.9 | ns |
| Top quality embryos (%) | 54.5 | 51.5 | ns |
| Endometrial thickness at OPU (mm) | 9.2 ± 2.1 | 9.0 ± 2.3 | ns |
Data are expressed as mean ± SD or percentage
aPatients with an endometrioma <4 cm during IVF or previously operated to remove an endometrioma