Table 1.
Screening tests for aneuploidy
| Screening test | Gestational age (weeks) | NT | PAPP-A | Free ß-hCG or hCG | MSAFP | uE3 | Inh A |
|---|---|---|---|---|---|---|---|
| First trimester | 9–14 | x | x | x | |||
| Second trimester triple | 15–22 | x | x | x | |||
| Second trimester quad | 15–22 | x | x | x | x | ||
| Full integrated | First trimester tests at 9–14, followed by Second trimester tests at 15–22 weeks | x | x | x | x | x | x |
| Serum integrated | x | x | x | x | x | ||
| Step-wise sequential | x | x | x | x | x | x |
NT ultrasound assessment of nuchal translucency, PAPP-A pregnancy-associated plasma protein A, ß-hCG beta human chorionic gonadotropin, MSAFP maternal serum alpha-fetoprotein, uE3 unconjugated estriol, Inh A, inhibin A