Figure 2. Knockdown of Elp3 inhibits cranial neural crest migration in Xenopus.

(a–f) Elp3 MO (25 ng) with or without Elp3 mRNA (0.2 ng) was injected into one cell of four-cell-stage embryos, and whole-mount in situ hybridization with probes for neural crest markers was processed at St.19–21. LacZ mRNA was co-injected to trace the injected sides (stained red on the right sides). (g) Percentages of embryos with reduced migration of neural crest as shown in (a–f). The results are from three independent experiments (error bars represent SDs).