Table 1.
Measures | Syndromes | Symptoms | Frequency (Duration) | Onset | |
---|---|---|---|---|---|
Clinical High Risk | SIPS2 | Attenuated Positive Symptom Syndrome (APSS) |
1 or more elevated sub-threshold positive symptom |
≥ 1x/week in the past month. | Past year or worsened compared to 1 year ago |
Brief Intermittent Psychotic Syndrome (BIPS) |
Briefly and recently met psychotic threshold on one or more positive symptom |
1x/month (Present at least several minutes a day) up to 4x/week |
Past 3 months | ||
Genetic Risk and Decline (GRD) |
Schizotypal Personality Disorder Diagnosis or 1st degree relative with a psychotic disorder and a current Global Assessment of Functioning (GAF) score at least 30% lower than 12 months ago |
||||
CAARMS19 | Attenuated Psychosis Group (Subthreshold Intensity) (APG) Attenuated Psychosis Group (Subthreshold Frequency) |
Elevated sub-threshold Unusual Thought Content (UTC), Non-Bizarre Ideas (NBI), Disorganized Speech (DS) or Perceptional Abnormalities (PA) and a 30% drop in SOFAS in the past year or a SOFAS ≤ 50 for the past year |
1x/month to 2x/week (> 1 hour per occasion) or 3- 6x/week (<1 hour per occasion) to continuous (for at least a week) |
Past 12 months but no more than 5 years ago |
|
Psychotic intensity on UTC or NBI or DS or Severe/Psychotic intensity on PA and a 30% drop in SOFAS in the past year or SOFAS ≤ 50 for the past year |
1x/month to 2x/week (> 1 hour per occasion) or 3- 6x/week (<1 hour per occasion) |
Past 12 months but < 5 years |
|||
Brief Limited Intermittent Psychotic Symptoms (BLIPS) |
Psychotic intensity on UTC or NBI or DS or Severe/Psychotic intensity on PA and a 30% drop in SOFAS in the past year or a SOFAS ≤ 50 for the past year |
3-6x/week (>1 hour per occasion) or daily (<1 hour per occasion) to continuous (for at least a week) |
Occurred during the last 12 months |
||
Vulnerability Group |
Schizotypal Personality Disorder Diagnosis or 1st degree relative with a psychotic disorder and a 30% drop in SOFAS in the past year or a SOFAS < 50 for the past year |
||||
Basic Symptoms | SPI-A20 | Cognitive Disturbances (COGDIS) |
At least 2 of the following: (Inability to Divide Attention; Thought Interference; Thought Pressure; Thought Blockages; Disturbance of Receptive Speech; Disturbance of Expressive Speech; Unstable Ideas of Reference; Disturbances of Abstract Thinking; Captivation of Attention by Details of the Visual Field) |
Weekly to daily | Last 3 months and 1st occurrence more than 12 months ago |
Note: SIPS = Structured Interview for Psychosis-Risk Syndromes; CAARMS = Comprehensive Assessment of At-Risk Mental States; SPI-A = Schizophrenia Prediction Instrument for Adults; SOFAS: Social and Occupational Functioning Assessment Scale