FIG. 1.

Schematic of the image processing routes investigated for the analysis of scaffold transport characteristics. Method A, Flood Fill, identifies the largest connected group of pore space voxels. Method B, three-dimensional (3D) Shrink-Wrap, identifies the accessible volume for a virtual object of defined diameter, traveling from the outside of the dataset. Method C, Directional Shrink-Wrap, is a variation of Method B, in which the virtual object can only access the scaffold interior from one surface. Method D, Percolation Diameter, describes the largest sphere that can travel to infinite distance through the scaffold in a direction of interest, calculated by measurement of accessible distance as a function of virtual object diameter. Color images available online at www.liebertpub.com/tec