Skip to main content
. 2016 May 18;6:26181. doi: 10.1038/srep26181

Figure 6. Pharmacological properties of evoked responses.

Figure 6

(A) Typical evoked responses from each of 64 electrodes following a single test stimulus at 33–36 WIV. Red square shows stimulus site (electrode 33). (B) Typical evoked responses before (top) and after the administration of the indicated neurotransmitter receptor agonist or antagonist at 33–36 WIV. Red triangle shows stimulus time and stimulus artifacts. (C) Post-stimulus time histogram (PSTH) (Sum of 10 individual responses at 64 electrodes, bin size = 1 ms) at 33–36 WIV. Blue and red indicate before and after drug administration, respectively. (D) Ratio of the number of evoked spikes after versus before drug administration at 10–15 WIV (gray) and 33–36 WIV (black) (n = 3 MEA dishes, *p < 0.05). (E) The ratio of evoked burst duration after versus before drug administration. (n = 3 MEA dishes, *p < 0.05).