Table 2.
PIs in PI based regimens | NNRTIs in NNRTI based regimens | NRTIs in PI or NNRTI based regimens | ||||
---|---|---|---|---|---|---|
1st | 2nd | 1st | 2nd | 1st | 2nd | |
1999–2001 | Nelfinavir (63%) | Indinavir/RTV (27%) | Efavirenz (95%) | Nevirapine (4%) | 3TC/ZDV (45%) | Stavudine (18%) |
2002–2004 | Lopinavir/RTV (73%) | Atazanavir/RTV (20%) | Efavirenz (90%) | Nevirapine (10%) | Lamivudine (25%) | Tenofovir (24%) |
2005–2007 | Atazanavir/RTV (52%) | Lopinavir/RTV (25%) | Efavirenz (100%) | FTC/TDF (48%) | 3TC/ABC (19%) | |
2008–2010 | Atazanavir/RTV (48%) | Darunavir/RTV (40%) | Efavirenz (98%)a | FTC/TDF (53%) | 3TC/ABC (22%) | |
2010–2012 | Darunavir/RTV (57%) | Atazanavir/RTV (37%) | Efavirenz (100%) | FTC/TDF (76%) | 3TC/ABC (12%) |
The other 2% NNRTIs in the 2008-2010 period correspond to Etravirine.
FTC/TDF, fixed dose combination of Emtricitabine and Tenofovir; RTV, Ritonavir; 3TC/ABC, fixed dose combination of Lamivudine and Abacavir; 3TC/ZDV, fixed dose combination of Lamivudine and Zidovudine.