Table 4.
Percent FIB-4 Difference by Hepatitis C Infection, Alcohol, and ART Class Adjusted for Age, Sex, and Race, Compared to the Reference Group (Hepatitis C Negative, Moderate Drinkers, NNRTI ART Regimen)
| Hepatitis C negative | Hepatitis C positive | |||||
|---|---|---|---|---|---|---|
| ΔFIB-4 | (95% CI) | p Value | ΔFIB-4 | (95% CI) | p Value | |
| Drinking category* | ||||||
| NNRTI nondrinker | 1.08% | (−14.05;18.88%) | 0.897 | 66.99% | (40.15;98.98%) | <0.001 |
| NNRTI moderate (ref.) | 0 (ref.) | 35.81% | (6.25;73.59%) | 0.004 | ||
| NNRTI hazardous | 4.06% | (−21.27;37.56%) | 0.780 | 70.32% | (26.96;128.48%) | 0.001 |
| PI nondrinker | 11.95% | (−5.63;32.80%) | 0.195 | 68.90% | (41.84;101.12%) | <0.001 |
| PI moderate | 3.24% | (−13.72;23.54%) | 0.728 | 75.09% | (37.46;123.02%) | <0.001 |
| PI hazardous | 44.95% | (4.74;100.60%) | 0.025 | 68.73% | (26.98;124.21%) | <0.001 |
*
p Value represents comparison between each group and the reference (hepatitis C negative, moderate drinkers on NNRTI based regimens).